Clinical Efficacy Testing
Substantiate Your Claims
Skin Hydration & Barrier Studies
Clinical studies designed to assess hydration/moisturization and skin barrier function through standardized instrumental measurements.
In addition to statistical analysis of instrumental measurements, studies may also include before-and-after HD photography and self-assessment questionnaires to support and validate subjective claims.

Study Characteristics
- Typically 20–30 subjects (customizable)
- Short-term (from immediate up to 72h) and/or long-term (weeks) evaluation
- Forearms (recommended) or facial measurements
- Self-assessment questionnaire-based evaluation
- Optional Dermatologist supervision
- Optional before/after lifestyle and/or VISIA photos
- Report delivery in 5 business days (express) or 12 (standard)

Evaluation Parameters & Methods
- Corneometry (skin hydration) – Corneometer® CM-825
- TEWL (skin barrier function) – Tewameter® TM 300

Typical Claim Support Areas
- Improves skin hydration
- Provides long-lasting moisturization
- All-day hydration (8h)
- Reduces dryness
- Improves the skin barrier (function)
- Reinforces and maintains the skin’s protective barrier
Anti-Aging Studies
Clinical studies designed to assess signs of aging, including wrinkles, skin firmness, elasticity or even age spots, through standardized instrumental measurement and/or expert clinical grading.
In addition to statistical analysis of instrumental measurements, studies may also include before-and-after HD photography and self-assessment questionnaires to support and validate subjective claims.

Study Characteristics
- Typically 20–50 subjects (customizable)
- Typical study duration of 28 days (4 weeks), 56 days (8 weeks) or 84 days (12 weeks)
- Self-assessment questionnaire-based evaluation
- Optional Dermatologist supervision
- Optional before/after lifestyle and/or VISIA photos
- Report delivery in 5 business days (express) or 12 (standard)

Evaluation Parameters & Methods
- Wrinkle reduction (crow’s feet) with 3D images and surface analysis – Antera 3D
- Clinical wrinkle grading – Bazin Scale / Bazin Atlas
- Skin elasticity and/or firmness – Cutometer®
- Usually combined with Skin Hydration & Barrier Studies

Typical Claim Support Areas
- Reduces the appearance of fine lines and wrinkles (with 3D images)
- Improves skin elasticity and/or firmness
- Promotes healthier, younger-looking skin
- Delays the visible signs of aging
- Enhances skin hydration
- Provides lasting moisturization
- Strengthens the skin barrier
Skin Tone Studies
Clinical studies designed to assess improvements in overall skin tone, including visible enhancements in skin radiance, evenness, and pigmentation through standardized instrumental measurement and/or expert clinical grading.
In addition to statistical analysis of instrumental measurements, studies may also include before-and-after HD photography and self-assessment questionnaires to support and validate subjective claims.

Study Characteristics
- Typically 20–50 subjects (customizable)
- Typical study duration of 28–56 days (4–8 weeks) or up to 84 days (12 weeks) if needed
- Self-assessment questionnaire-based evaluation
- Optional Dermatologist supervision
- Optional before/after lifestyle and/or VISIA photos
- Report delivery in 5 business days (express) or 12 (standard)

Evaluation Parameters & Methods
- Skin luminosity – Antera 3D / Clinical grading
- Pigmentation, melasma and dark spots – Antera 3D / Clinical grading
- Skin tone evenness – Antera 3D / Clinical grading
- Overall radiance / glow – Clinical grading

Typical Claim Support Areas
- Brightens the skin
- Enhances skin luminosity / glow
- Evens out skin tone
- Reduces the appearance of dark spots
- Reduces pigmentation and melasma
- Improves overall skin radiance
- Restores a healthy-looking complexion
Oily Skin Studies
Clinical studies designed to evaluate sebum production and support oil-control or mattifying claims. Standardized Sebumeter® measurements provide reliable quantitative data, while self-assessment questionnaires and before-and-after HD photography support and demonstrate subjective product performance.

Study Characteristics
- Typically 20–50 subjects (customizable)
- Instant or short-term (typically 2–8 hours) and/or long-term (up to 28 days [4 weeks] or 56 days [8 weeks]) evaluation
- Primarily facial measurements (cheeks and forehead)
- Self-assessment questionnaire-based evaluation
- Optional Dermatologist supervision
- Optional before/after lifestyle and/or VISIA photos
- Report delivery in 5 business days (express) or 12 (standard)

Evaluation Parameters & Methods
- Sebum/oil measurement – Sebumeter® SM 815
- Usually combined with Non-Comedogenicity Studies

Typical Claim Support Areas
- Reduces visible oiliness
- Controls excess sebum throughout the day
- Minimizes shiny appearance
- Helps skin appear smoother and less greasy
- Suitable for oily or acne-prone skin (if applicable)
Non-Comedogenic Studies
Clinical studies designed to assess non-comedogenicity, evaluating whether a product is likely to clog pores or contribute to comedone formation. Evaluation is based on expert clinical grading of comedones and other skin reactions. These studies are particularly relevant for oily or acne-prone skin formulations.

Study Characteristics
- Typically 30 subjects with oily or acne-prone skin (customizable)
- Minimum study duration of 28 days (4 weeks), with possible extension to 56 days (8 weeks)
- Facial area application
- Subject compliance and tolerance monitoring throughout the study
- Clinical evaluation with comedone/lesion count at baseline and end of study, assessed by a trained Dermatologist or expert grader
- Self-assessment questionnaire-based evaluation
- Report delivery in 5 business days (express) or 12 (standard)

Evaluation Parameters & Methods
- Expert clinical grading of comedones and visible pore blockage
- Often combined with Oily Skin Studies

Typical Claim Support Areas
- Non-comedogenic
- Does not clog pores
- Suitable for oily or acne-prone skin
- Dermatologically tested / supervised
- Well tolerated, even on problem-prone skin
- Helps maintain clear-looking skin